DHA-EE Research

◉  Summary Questions About DHA-EE in Zellweger’s


◉  Modulation of inflammation in brain: a matter of fat.                                                                                                                                    Akhlaq A. Farooqui , Lloyd A. Horrocks, Tahira Farooqui                                                                                                                                    Journal of Neurochemistry, January 25, 2007                                                                                                                        https://doi.org/10.1111/j.1471-4159.2006.04371.x


◉  Essential Dietary Bioactive Lipids in Neuroinflammatory Diseases. Antioxid Redox Signal.                                                                      Catani MV, Gasperi V, Bisogno T, Maccarrone M.                                                                                                                                            2018;29(1):37–60. doi:10.1089/ars.2016.6958                                                                              https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984567/?report=reader


◉  Dra. Manuela Martinez last published research, 2010. The Δ4-desaturation pathway for DHA biosynthesis is operative in the human species: Differences between normal controls and children with the Zellweger syndrome. Martinez et al. Lipids in Health and Disease 2010, 9:98 http://www.lipidworld.com/content/9/1/98                                                              http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949860/


◉  Docosahexaenoic acid mediates peroxisomal elongation, a prerequisite for peroxisome division. (2-2012) http://jcs.biologists.org/content/125/3/589.long#T1


◉  DHA is a key factor in stimulating brain-derived neurotrophic factor (BDNF) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208643/                                                  http://www.researchgate.net/publication/26695415                           https://www.ibp.ucla.edu/research/GomezPinilla/publications/Diet1457.pdf


◉  Noguer Visual Follow-Up in Peroxisomal-Disorder Patients Treated with Docosahexaenoic Acid Ethyl Ester http://www.ncbi.nlm.nih.gov/pubmed/19933185


◉  Martínez, Manuela, et al. “Therapeutic effects of docosahexaenoic acid ethyl ester in patients with generalized peroxisomal disorders.” The American Journal of Clinical Nutrition 71.1 (2000): 376s-385s. http://www.ncbi.nlm.nih.gov/pubmed/10618001 http://ajcn.nutrition.org/content/71/1/376s.full


◉  Zellweger’s Syndrome Restoring the DHA Levels in the Brains of Zellweger Patients, J Mol Neurosci.                                                      2001 Apr-Jun;16(2-3):309-16  http://www.ncbi.nlm.nih.gov/pubmed/11478386


◉  The fundamentals and practice of docosahexaenoic acid therapy in peroxisomal disorders, by M Martinez – ‎2000.  Current Opinion in Clinical Nutrition & Metabolic Care: March 2000 – Volume 3 – Issue 2 – pp 101-108.                    http://journals.lww.com/coclinicalnutrition/Abstract/2000/03000/The_fundamentals_and_practice_of_docosahexaenoic.4.aspx  Peroxisomal disorders and their treatment.                                                                                              http://www.momtahan.com/mmartinez/


◉  Two Studies, Two Products, Two Results  Investigates the difference in the Martinez studies and the Paker, et al. study.

Textbooks

◉  Enfermedades peroxisomales generalizadas: nuevas posibilidades terapeuticas, Martinez Cap 44;

 

◉  Enfermedades peroxisomales generalizadas: nuevo enfoque terapeutico, Cap.+68.+Dra.+Martinez;